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Biosensing - overview

Advanced Biosensing

The biosensing project is divided into two categories: development of ultrasensitive surface plamson resonance sensor and utilization of porous media for size-selective biosensing applications.

Ultrasensitive Surface Plasmon Resonance

Existing surface plasmon resonance (SPR) biosensors do not operate at their limits of sensitivity owing to technical noise and not to any fundamental limitations. The objective is to reach the limits of sensitivity by using active electronic noise suppression techniques integrated with sensor configurations that can operate at the fundamental limits of system noise.

Size Selective Porous Organosilicates

Mesoporous inorganic structured materials have the ability to capture smaller concentrations of target biomolecules. Such media could, in principle, both provide an exquisite level of sensor sensitivity and selectivity, as they provide high surface areas for increased attachment density of receptors, the surface energy and pore sizes (shapes) can be manipulated to provide physical selection of target substances by size, shape and morphology, and will provide a robust platform in harsh environments.