Sara Capponi  Sara Capponi photo         

contact information

Research Staff Member
Almaden Research Center, San Jose, CA, USA


Professional Associations

Professional Associations:  American Physical Society (APS)  |  Biophysical Society  |  Society for Industrial and Applied Mathematics



Sara Capponi is Research Staff Member in the department of Functional Genomics and Cellular Engineering at the IBM Almaden Research Center, where she leads the Cellular Engineering Lab. Her main interest is to understand how natural and artificial biological systems function combining structural biology with physics, mathematics, and computer science.

Dr. Capponi completed her Ph. D. studies in Physics at the Donostia International Physics Center in the Basque Country, Spain. Prior joining IBM Research at Almaden, Dr. Capponi worked as postdoctoral fellow at UC Irvine and at UC San Francisco. Her contributions span from studies on macromolecular systems such as membrane or viral proteins to works on water dynamics and structure. During her career, she made use of different computational approaches, including molecular dynamics, enhanced sampling techniques, agent-based models, and machine learning methods for data analysis.

Dr. Capponi is IBM PI and site director of the Center for Cellular Construction, an NSF Science and Technology Center in partnership with UC San Francisco, UC Berkeley, Stanford University, SF State University, and the SF Exploratorium. The center aims at developing an engineering discipline to design cells. 

For a complete list of publications, refer to