Ming L. Yu
Physical Review B
Microcontact printing of proteins proves to be an excellent means of directly patterning biomolecules on solid substrates. Monolayer quantities of protein equilibrated on the surface of a hydrophobic, elastomeric stamp are immobilized there to rinses with buffer. These biomolecules can nevertheless transfer with >99% efficiency from the stamp to a substrate after just 1 s of contact. This capability allows the simple creation of functional patterns of proteins at scales that involve the placement of < 1000 molecules in well-defined locations on a surface. The method is suited for the transfer of proteins of many different types onto hydrophilic or hydrophobic substrates.
Ming L. Yu
Physical Review B
J.K. Gimzewski, T.A. Jung, et al.
Surface Science
U. Wieser, U. Kunze, et al.
Physica E: Low-Dimensional Systems and Nanostructures
M.A. Lutz, R.M. Feenstra, et al.
Surface Science