Govind Kaigala  Govind Kaigala photo       

contact information

Research Staff Member
IBM Research Laboratory - Zurich, Rueschlikon, Switzerland



Focusing analytes from 50uL into 500 pL: On-chip focusing from large sample volumes using isotachophoresis
X. F. van Kooten, M. Truman-Rosentsvit, G.V. Kaigala, M. Bercovici
Scientific Reports7, 2017

Isotachophoresis-Based Surface Immunoassay
F. Paratore, T. Zeidman Kalman, T. Rosenfeld, G. V. Kaigala, M. Bercovici
Analytical Chemisty 89(14), 7373-7381, 2017

Tissue Lithography: Microscale Dewaxing to Enable Retrospective Studies on Formalin-Fixed Paraffin Embedded (FFPE) Tissue Sections
J. F. Cors, A. Kashyap, A. Fomitcheva Khartchenko, P. Schraml, and G. V. Kaigala
PLoS One, 2017


Hydrodynamic thermal confinement: creating thermo-chemical microenvironments on surfaces
J. F. Cors, A. Stucki, and G. V. Kaigala
Chemical Communications52, 13035-13038, 2016

Centimeter-scale surface interactions using hydrodynamic flow confinements
D. P. Taylor, I. Zeaf, R. D. Lovchik, and G. V. Kaigala
Langmuir 32(41), 10537-10544, 2016

Rapid subtractive patterning of live cell layers with a microfluidic probe
A. Kashyap, J. C. Cors, R. D. Lovchik, and G. V. Kaigala
J. Vis. Exp pp. 115, e54447, 2016

Selective local lysis and sampling of live cells for nucleic acid analysis using a microfluidic probe
A. Kashyap, J. Autebert, E. Delamarche and G. V. Kaigala
Scientific Reports6, 29579, 2016

Delivery of minimally dispersed liquid interfaces for sequential surface chemistry
N. Ostromohov, M. Bercovici, and G. V. Kaigala
Lab Chip, special issue on emerging investigators,16, 3015-3023, 2016
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Convection-enhanced biopatterning with hydrodynamically confined nanoliter volumes of reagents
J. Autebert, J. Cors, D. Taylor, and G. V. Kaigala
Anal. Chem. 88(6), 3235-3242, 2016
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Micro fluorescence in situ hybridization (µFISH) for spatially multiplexed analysis of a cell monolayer
D. Huber, J. Autebert, and G. V. Kaigala
Biomedical Microdevices 18(40), 2016


Passive removal of immiscible spacers from segmented flows in a microfluidic probe
X. F. Kooten, J. Autebert and G.V. Kaigala
Appl. Phys. Lett.106, 074102, 2015

Lab-on-a-chip devices. How to close and plug the lab?
Y. Temiz, R.D. Lovchik, G.V. Kaigala and E. Delamarche
Microelectronic Engineering132, 156-175, 2015


The floating Microfluidic Probe (fMFP): Distance control between probe and sample using hydrodynamic levitation
M. Hitzbleck, G.V. Kaigala, E. Delamarche and R.D. Lovchik
Applied Physics Letters104, 263501, 2014

A compact and versatile microfluidic probe for local processing of tissue sections and biological specimens
J. F. Cors, R. D. Lovchik, E. Delamarche, and G. V. Kaigala
Review of Scientific Instruments85, 034301, 2014

Hierarchical hydrodynamic flow confinement: efficient use and retrieval of chemicals for microscale biochemistry on surfaces
J. Autebert, A. Kashyap, R. D. Lovchik, E. Delamarche and G.V. Kaigala
Langmuir 30(12), 2014


Microfluidics in the "Open Space" for Performing Localized Chemistry on Biological Interfaces
G. V. Kaigala, R. D. Lovchik and E. Delamarche
Angewandte Chemie (invited review), 2012

Micro-immunohistochemistry using a microfluidic probe
R. D. Lovchik, G. V. Kaigala, M. Georgiadis and E. Delamarche
Lab on a Chip12, 1040-1043, 2012
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Nonlinear controller designs for thermal management in PCR amplification
J. Jiang, G. V. Kaigala, H. J. Marquez and C. J. Backhouse
IEEE Transactions on Control System Technology 20(1), 11-30, 2012


The Vertical Microfluidic Probe
G. V. Kaigala, R. D. Lovchik, U. Drechsler and E. Delamarche
Langmuir27, 5686-5693, 2011

Rapid detection of urinary tract infection using and isotachaphoresis and molecular beacons
M. Bercovici, G. V. Kaigala (co-first author), K. Mach, C. Han, J. Liao and J. G. Santiago
Analytical Chemistry83, 4110-4117, 2011


Miniaturized system for isotachophoresis assays
G. V. Kaigala, M. Bercovici, M. Behnam, D. Elliott, J. G. Santiago and C. J. Backhouse
Lab on a Chip10, 2242-2250, 2010

Fluorescent carrier ampholytes assay for portable, label-free detection of chemical toxins in tap water
M. Bercovici, G. V. Kaigala, C. J. Backhouse and J. G. Santiago
Analytical Chemistry82, 1858-1866, 2010

A scalable and modular lab-on-a-chip genetic analysis instrument
G. V. Kaigala, M. Behnam, A. C. E. Bidulock, C. Bargen, R. W Johnstone, D. G. Elliott and C. J. Backhouse
The Analyst, 1606-1617, 2010
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Integrated circuit-based instrumentation for microchip capillary electrophoresis
M. Behnam, G. V. Kaigala (co-first author), M. Khorasani, S. Martel, D. G. Elliott and C. J. Backhouse
IET Nanobiotechnology4, 91-101, 2010

System design and modeling of a time-varying nonlinear temperature controller for microfluidics
G. V. Kaigala, J. Jiang, C. J. Backhouse, H. J. Marquez
IEEE Transactions on Control System Technology18, 521-530, 2010


Inexpensive, universal serial bus-powered and fully portable lab-on-a-chip-based capillary electrophoresis instrument
G. V. Kaigala, M. Behnam, C. Bliss, M. Khorasani, S. Ho, D. G. Elliott, J. McMullin, and C. J. Backhouse
IET Nanobiotechnology3, 1-7, 2009


Strategies for enhancing the speed and integration of microchip genetic amplification
V. N. Hoang, G. V. Kaigala, A. Atrazhev, L. M. Pilarski, C. J. Backhouse
Electrophoresis, special issue on DNA sequencing,29, 4684-4694, 2008

Elemental analysis using micro Laser-induced Breakdown Spectroscopy (micro-LIBS) in a microfluidic platform
Y. Godwal, G. V. Kaigala (co-first author), V. Hoang, S-L. Lui, C. Backhouse, Y. Tsui, R. Fedosejevs
Optics Express16, 12435-12445, 2008
(selected for publication to the Virtual Journal of Biomedical Optics)

An integrated CMOS high voltage supply for true Lab-on-a-Chip
M. Behnam, G. V. Kaigala, M. Khorasani, P. Marshall, C. J. Backhouse, D. G. Elliott
Lab on a Chip8, 1524-1529, 2008

Electrically controlled microvalves to integrate microchip polymerase chain reaction and capillary electrophoresis
G. V. Kaigala, V. Hoang and C. J. Backhouse
Lab on a Chip8, 1071-1078, 2008
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Readily integrated, electrically-addressable microvalves
W. H. Song, J. Kwan, G. V. Kaigala, V. N. Hoang and C. J. Backhouse
Journal of Micromechanics and Microengineering18, 045009, 2008

An inexpensive and portable microchip-based platform for integrated RT-PCR and capillary electrophoresis
G. V. Kaigala, V. Hoang, A. Stickel, J. Lauzon, D. Manage, L. M. Pilarski, C. J. Backhouse
The Analyst133, 331-338, Cover page, one of the , 2008


Microfluidic platform for Single Nucleotide Polymorphism genotyping of the Thiopurine S-Methyltransferase gene to evaluate risk for adverse drug events
J. Chowdhury, G. V. Kaigala (co-first author), S. Pushpakom, J. Lauzon, A. Makin, A. Atrazhev, A. Stickel, W. G. Newman, C.J. Backhouse and L.M. Pilarski
J. Molecular Diagnostics9, 521-529, 2007

Microfluidic chips for detecting the t(4;14) translocation and monitoring disease during treatment using Reverse Transcriptase-Polymerase Chain Reaction analysis of IgH-MMSET hybrid transcripts
J. VanDijken, G. V. Kaigala (co-first author), J. Lauzon, A. Atrazhev, B. J. Taylor, T. Reiman, A. R. Belch, C J. Backhouse, L. M Pilarski
J. Molecular Diagnostics9, 358-367, 2007

FISH and chips: Chromosomal analysis on microfluidic platforms
V. J. Sieben, C. S. Debes-Marun, P. M. Pilarski, G. V. Kaigala, L. M. Pilarski, C. J. Backhouse
IET Nanobiotechnology1, 25-37, 2007

Rapid prototyping of microfluidic devices with a wax printer
G. V. Kaigala, S. Ho, R. Penterman, C. J. Backhouse
Lab on a Chip7, 384-387, 2007